are small cell-derived membrane vesicles often used to study drug-metabolizing enzymes in cells. They are particularly useful for studying hepatic drug metabolism and can be obtained by ultracentrifugation of cell homogenates.
is a subcellular fraction obtained from the homogenate of liver tissues or other tissues rich in metabolic enzymes. It is used to study drug metabolism in vitro, particularly to evaluate the biotransformation of chemical compounds and drugs.
are the principal cells of the liver, responsible for many metabolic functions, including drug metabolism. They are widely used in drug metabolism studies to evaluate the biotransformation of drugs and chemical compounds, as well as to study potential liver toxicity.
Slices, or tissue slices, are sections of biological tissue, often used to study pharmacological responses, toxicity or other effects of chemical compounds or drugs on specific tissues. Liver slices are commonly used to study drug biotransformation and metabolic activity in a context closer to that of intact biological tissue.